A new perspective on anthropogenic nitrogen loss mitigation strategies: Integrated control via sustainable regional integration.

Unregulated regional integrated development disrupts the reactive nitrogen (Nr) cycle, adding complexity to anthropogenic Nr environmental losses. The objective of this study was to establish a framework for mitigating anthropogenic Nr loss through a new regional integration perspective by analyzing anthropogenic Nr loss and integrated control strategies in the Yangtze River Delta (YRD) region from 2011 to 2020. The results revealed that the total Nr loss in the YRD ranged from 1780.7 to 1972.0 Gg N yr-1. Re-linking cropland and livestock is crucial for reducing Nr loss, as they act as the main sources of Nr loss. Spatial analysis at the regional scale revealed that regional integration has led to a dispersion of Nr loss, while uneven development among cities has resulted in a westward shift of 8.6 km in the Nr loss centroid, suggesting the need for the implementation of collaborative governance and integrated environmental regulation in the YRD. At the city scale, 27 cities were clustered into six types based on the similarity of Nr loss structural characteristics, allowing for the development of targeted reduction policies based on the specific Nr structural characteristics of each city. The results of driver and mitigation potential analysis indicated the feasibility of achieving the shared goal of sustainable regional integration and the application of optimal mitigation strategies in different cities and the YRD. Overall, the new-perspective framework established in this study provides valuable references for sustainable Nr management in the context of regional integration.

Micropollutant rejection by nanofiltration membranes: A mini review dedicated to the critical factors and modelling prediction.

Nanofiltration (NF) membranes, extensively used in advanced wastewater treatment, have broad application prospects for the removal of emerging trace organic micropollutants (MPs). The treatment performance is affected by several factors, such as the properties of NF membranes, characteristics of target MPs, and operating conditions of the NF system concerning MP rejection. However, quantitative studies on different contributors in this context are limited. To fill the knowledge gap, this study aims to assess critical impact factors controlling MP rejection and develop a feasible model for MP removal prediction. The mini-review firstly summarized membrane pore size, membrane zeta potential, and the normalized molecular size (λ = rs/rp), showeing better individual relationships with MP rejection by NF membranes. The Lindeman-Merenda-Gold model was used to quantitatively assess the relative importance of all summarized impact factors. The results showed that membrane pore size and operating pressure were the high impact factors with the highest relative contribution rates to MP rejection of 32.11% and 25.57%, respectively. Moderate impact factors included membrane zeta potential, solution pH, and molecular radius with relative contribution rates of 10.15%, 8.17%, and 7.83%, respectively. The remaining low impact factors, including MP charge, molecular weight, logKow, pKa and crossflow rate, comprised all the remaining contribution rates of 16.19% through the model calculation. Furthermore, based on the results and data availabilities from references, the machine learning-based random forest regression model was trained with a relatively low root mean squared error and mean absolute error of 12.22% and 6.92%, respectively. The developed model was then successfully applied to predict MPs' rejections by NF membranes. These findings provide valuable insights that can be applied in the future to optimize NF membrane designs, operation, and prediction in terms of removing micropollutants.

Prevalence of suicide ideation among HIV/AIDS patients in China: A systematic review and meta-analysis.

Objective: A systematic review and meta-analysis was performed to evaluate the prevalence of suicide ideation among HIV/AIDS patients in China. Methods: Systematic search of CNKI, Wanfang, China biology medicine database, Weipu, EMBASE, Web of science and PubMed for studies related to the suicide ideation of HIV/AIDS patients. The incidence of suicide ideation of HIV / AIDS patients in China was investigated by meta-analysis. Results: A total of 16 studies were included (n = 6,174). The incidence of suicidal ideation in HIV/AIDS patients was 30.6% (95%CI: 21.4-39.9%). The results of subgroup analysis showed that the incidence of suicidal ideation in male was 36.1%, which was higher than that in female (32.8%), homosexual patients (39.7%) higher than heterosexual patients (27.1%), 2013-2021 survey (35.2%) higher than 2003-2012 survey (26.5%), the unmarried patients (39.6%) were higher than the married patients (34.5%), the patients diagnosed >1 year (28.4%) were higher than the patients diagnosed <1 year (27.6%), and the depression patients (34.3%) were higher than patients without depression (20.5%) and CD4 cell counts ≤200 cells/ul group (20.6%) were higher than those in >400 cells/ul group (19.8%). Conclusion: The incidence of suicide ideation in HIV/AIDS patients in China is relatively high.

Evaluating the anthropogenic nitrogen emissions to water using a hybrid approach in a city cluster: Insights into historical evolution, attribution, and mitigation potential.

Anthropogenic reactive nitrogen (Nr) emissions from agricultural production and food consumption in city clusters have caused water quality degradation and scarcity. In this study, anthropogenic Nr emissions to the water environment were quantitatively evaluated in the Yangtze River Delta city cluster from 2011 to 2020 using coupling nitrogen (N) flow analysis and the grey water footprint (GWF) method. The spatiotemporal characteristics of the GWF and the relative contributions of natural and human factors to the water pollution level (WPL) were analyzed. The results showed that from 2011 to 2020, the total N-related GWF decreased by 12.1 %, mainly driven by reduced fertilizer application and livestock numbers. In 2020, the primary pollution source changed from livestock to humans; however, non-point sources still dominated the GWF. The spatial clustering trend of the GWF was significant: high and low GWF were mainly concentrated in the northeast and southwest regions, respectively. From 2011 to 2020, the mean center of the GWF moved west due to the decrease and increase in the eastern and western regions, respectively, supporting the pollution haven hypothesis. The WPL ranged from 2.67 to 5.03 and fluctuated due to variations in precipitation. The relative contributions of natural and human factors to the WPL evolution were 72.9 % and 27.1 %, respectively. According to the scenario analysis, increasing the N use efficiency to 50 %, manure recycling rate to 80 %, and sewage treatment rate in urban and rural regions to 98 % and 40 %, respectively, could decrease GWF by 39.6 %. The present study establishes an open framework to evaluate anthropogenic N emissions to water, and the outcomes provide valuable references for sustainable N management in city clusters.

Evaluation of depression status and its influencing factors in convalescent elderly patients with first-episode stroke.

OBJECTIVE: To investigate the occurrence and the influencing factors of post-stroke depression (PSD) in first-episode stroke. METHODS: A total of 350 elderly stroke patients who were admitted to Wuxi Central Rehabilitation Hospital for the first time from January 2020 to December 2020 were enrolled in this study. The Hamilton Depression Scale (HAMD) was used to evaluate the depression status of stroke patients. The sociodemographic data, clinical symptoms, social environment and behavioral patterns of the patients were collected to analyze the related factors of depression after stroke through SPSS 20.0 software. RESULTS: The incidence of PSD was 45.71%. There were statistical differences among different gender, lesion nature, lesion location, smoking, hypertension, diabetes, hospitalization enpenses, season of onset, BMI index, NIHSS score, barthel index score, blood pressure variation coefficient and other factors (p = 0.000). Post-stroke depression score was positively correlated with NIHSS score and coefficient of variation of systolic blood pressure (r = 0.935, p = 0.000; r = 0.921, p = 0.000), and negatively correlated with barthel index score (r = -0.964, p = 0.000). Through multivariate Logistic regression analysis, it was found that male (OR=8.624, 95%CI: 5.672-11.715), cerebral infarction (OR=2.561, 95%CI: 1.256-3.567), and the right side lesion (OR=1.933, 95%CI: 1.024-3.026), smoking (OR=2.457, 95%CI: 1.611-3.625), onset in autumn and winter (OR=2.049, 95%CI: 1.201-2.919), high BMI (OR=2.461, 95%CI): 1.426-3.432) were risk factors for depression after stroke, and low SBPV (OR=0.567, 95%CI: 0.352-0.758) and low NISHH score (OR=0.256, 95%CI: 0.105-0.486) were the protective factor for subsequent depression of stroke. CONCLUSION: Males, smoking, patients with onset in autumn and winter, lesions on the right side, high BMI, high NISHH score and high systolic blood pressure variation were closely related to PSD, which should be paid for attention for such patients to prevent the occurrence of PSD and take intervention measures.

Investigation of Mental Health Literacy and Status of Residents During the Re-Outbreak of COVID-19 in China.

Introduction: The current field of research on the impact of COVID-19 on mental health was mostly limited to the evaluation of the first round of the epidemic, few reports focused on the impact of the re-emergence of COVID-19. This study aimed to investigate the mental health literacy and status of residents during the re-outbreak of COVID-19 in China. Methods: The basic information sheet, health literacy survey scale, physical health questionnaire-9 (PHQ-9), generalized anxiety disorder-7 (GAD-7), insomnia severity index (ISI), and Alzheimer dementia 8 (AD8) were applied to evaluate the mental health literacy, mental health status and elderly cognitive function, and χ2 test was applied for analysis of the difference between different groups. Results: A total of 2,306 participants were involved in this study, of which 734 people completed the mental health literacy survey. The qualified rate of mental health literacy was 6.4%. The difference is statistically significant. A total of 1,015 people completed the survey of mental health status, the prevalence of depressive symptoms was 8.87%, the monthly income of different families (χ2 = 13.96, P = 0.01), the self-assessed health status (χ2 = 128.56, P < 0.05), the presence or absence of chronic diseases (χ2 = 4.78, P = 0.03), among all which the difference was statistically significant; the prevalence of anxiety symptoms was 3.84%, different regions (χ2 = 12.26, P < 0.05), occupations (χ2 = 11.65, P < 0.05), household monthly income (χ2 = 12.65, P = 0.01), self-rated health status (χ2 = 151.11, P < 0.05), and chronic diseases (χ2 = 7.77, P = 0.01), among all which the differences were statistically significant. The prevalence of insomnia symptoms was 7.98%, different age (χ2 = 18.45, P < 0.05), region (χ2 = 5.11, P = 0.02), monthly household income (χ2 = 12.68 P = 0.01), and self-assessed health status (χ2 = 91.71, P < 0.05), in which there was a statistically significant difference between those with or without chronic diseases (χ2 = 3 3.25, P < 0.05). A total of 557 elderly people over 65 years old completed the cognitive dysfunction screening, in which the prevalence of cognitive dysfunction was 17.41%, and the difference was statistically significant at the different self-assessed health status (χ2 = 96.24, P < 0.05) and with or without chronic diseases (χ2 = 107.09, P < 0.05). Conclusion: The mental health literacy and status of residents have not improved significantly during the second outbreak of the epidemic, indicating that under the normalization of epidemic prevention and control, more attention should be paid to the mental health of residents, and targeted health education and psychological intervention should be carried out to avoid relative adverse events.

Nitrogen flow in the food production and consumption system within the Yangtze River Delta city cluster: Influences of cropland and urbanization.

Intensive anthropogenic activities associated with the food production and consumption system (FPC) drive massive reactive nitrogen inputs to city clusters resulting in serious nitrogen (N) pollution. We conducted a substance flow analysis to examine N flows in the FPC within the Yangtze River Delta city cluster from 2011 to 2019. The total N input and output showed parabolic downward trends, with decreases from 4008.27 to 3472.57 Gg N yr-1 and 3518.65 to 3061.29 Gg N yr-1, respectively; chemical fertilizer (54.7%-57.3%) and N loss (87.1%-90.9%) were the primary components of N input and output, respectively. The decreased total N input was related to reductions in chemical fertilizers and livestock numbers. However, a notable increase in N input to the human subsystem was observed, and urbanization was associated with increased N inputs within the human subsystem via higher amounts of food N consumed per capita and proportions of animal-based food N consumed. Total N loss initially increased then decreased; Nantong, Jiaxing, Shanghai, Yancheng, Taizhou, and Yangzhou were the top six cities in N loss intensity. The proportion of cultivated land area, livestock numbers per unit area, and population density were important factors influencing the spatial heterogeneity of N loss intensity. Twenty-six cities were divided into six groups based on their N loss composition, and various N management strategies were proposed. This study highlights the strong influences of cropland and urbanization on N flows within the FPC, which can be used as a reference for N management at a city cluster scale.

Utilization of coal fly ash waste for effective recapture of phosphorus from waters.

Reutilization of the waste by-products from industrial and agricultural activities is crucially important towards attainment of environmental sustainability and the 'circular economy'. In this study, we have developed and evaluated a sustainably-sourced adsorbent from coal fly ash, which was modified by a small amount of lanthanum (La-FA), for the recapture of phosphorous (P) from both synthetic and real natural waters. The prepared La-FA adsorbent possessed typical characteristic diffraction peaks similar to zeolite type Na-P1, and the BET surface area of La-FA was measured to be 10.9 times higher than that of the original FA. Investigation of P adsorption capability indicated that the maximum adsorption (10.8 mg P g-1) was 6.14 times higher than that (1.8 mg P g-1) of the original fly ash material. The ζ potentials measurement and P K-edge X-ray Absorption Near Edge Structure (XANES) spectra demonstrated that P was bonded on La-FA surfaces via an adsorption mechanism. After applying the proposed adsorbent to real lake water with La/P molar ratios in the range from 0.5:1 to 3:1, the La-FA adsorbent showed the highest phosphate removal ability with a La/P molar ratio 1:1, and the P adsorption was similar to that performance with the synthetic solution. Moreover, the La-FA absorbent produced a negligible effect on the concentrations of total dissolved nitrogen (TDN), NH4+-N and NO3--N in water. This study thus provides a potential material for effective P recapture and details of its operation.

A model to determine the lake nutrient standards for drinking water sources in Yunnan-Guizhou Plateau Ecoregion, China.

Lake eutrophication (LE) has become an increasingly severe environmental problem recently. However, there has been no nutrient standard established for LE control in many developing countries such as China. This study proposes a structural equation model to assist in the establishment of a lake nutrient standard for drinking water sources in Yunnan-Guizhou Plateau Ecoregion (Yungui Ecoregion), China. The modeling results indicate that the most predictive indicator for designated use-attainment is total phosphorus (TP) (total effect = -0.43), and chlorophyll a (Chl-a) is recommended as the second important indicator (total effect = -0.41). The model is further used for estimating the probability of use-attainment associated with lake water as a drinking water source and various levels of candidate criteria (based on the reference conditions and the current environmental quality standards for surface water). It is found that these candidate criteria cannot satisfy the designated 100% use-attainment. To achieve the short-term target (85% attainment of the designated use), TP and Chl-a values ought to be less than 0.02 mg/L and 1.4 microg/L, respectively. When used as a long-term target (90% or greater attainment of the designated use), the TP and Chl-a values are suggested to be less than 0.018 mg/L and 1 microg/L, respectively.